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低コレステロール血症は死亡率を上げる・低栄養など除外しても

Iso H, Naito Y, Kitamura A, Sato S, Kiyama M, Takayama Y, Iida M,
Shimamoto T,Sankai T, Komachi Y.
Serum total cholesterol and mortality in a Japanese population.
J Clin Epidemiol. 1994 Sep;47(9):961-9.
PMID: 7730912 [PubMed - indexed for MEDLINE]

日本人のコホート研究
がんなどがありすでに状態の悪い人でコレステロールが低いという因果の逆転をある程度補正するために追跡開始後5年間の死亡は除外して解析しても、低コレステロールで死亡率上がる

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